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Tracheobronchial and Parenchymal Amyloidosis

Imaging findings

Chest CT shows patchy, nodular, and calcified mucosal thickening along the tracheobronchial tree. Also present are a few scattered, thin-walled parenchymal lung cysts. Biopsy and mass spectroscopy confirmed AL kappa light-chain amyloidosis.

Key takeaways

Although amyloidosis is often categorized as either localized tracheobronchial disease or parenchymal nodular/cystic disease, these patterns can occasionally coexist. Amyloidosis should be included in the differential diagnosis for calcified airway thickening and associated parenchymal lung cysts.

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