Pulmonary Aspergilloma in Healed Post-Tuberculosis Cavity
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Imaging findings
Chest radiograph shows progression from fibrocalcific scarring, volume loss, and bronchiectasis in the right upper lobe (consistent with healed tuberculosis) to the development of a new soft tissue nodule within this area. CT confirms a well-defined filling defect (aspergilloma) inside a thick-walled chronic cavity, surrounded by established bronchiectasis and calcification.
Key takeaways
This case illustrates a pulmonary aspergilloma developing within a pre-existing chronic cavity, a common sequela of healed tuberculosis, especially in regions with high TB prevalence. The aspergilloma causes local inflammation and can lead to symptoms like increased sputum production and cough. This serves as a reminder that worldwide, tuberculosis is the leading cause of chronic cavitary disease predisposing to aspergilloma formation.
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