Microscopic Polyangiitis with Diffuse Alveolar Hemorrhage and Pulmonary Fibrosis
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Imaging findings
Diffuse, widespread central ground-glass opacities with areas of consolidation, involving all lung lobes, consistent with diffuse alveolar hemorrhage. Additionally, there were areas of fibrosis, cystic change, and bronchiectasis with volume loss in the right lower lobe.
Key takeaways
Microscopic polyangiitis can present with diffuse alveolar hemorrhage and is often associated with positive p-ANCA and anti-peroxidase antibodies. A significant percentage of these patients (around 30%) can also develop pulmonary fibrosis, possibly due to recurrent hemorrhage or an association with NSIP.
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