Organizing Pneumonia Progressing to Fibrosis in Rheumatoid Arthritis
Imaging findings
Initial CT reveals a classic pattern of organizing pneumonia with peripheral consolidation and diffuse ground glass opacities. Over time, despite treatment with high-dose steroids and celep, the findings evolved from predominantly consolidative/ground glass to a diffuse pattern of fibrosis, indicating progression of the organizing pneumonia to a fibrotic interstitial lung disease.
Key takeaways
Organizing pneumonia, especially when associated with systemic inflammatory processes like rheumatoid arthritis, can progress to diffuse fibrosis over time, potentially evolving into a pattern consistent with fibrotic NSIP. This highlights the dynamic nature of these inflammatory lung diseases and the potential for fibrotic transformation. Biopsy may be needed to confirm the initial organizing pneumonia.
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