CTICasesLymphoid Interstitial Pneumonia (LIP) related to Sjögren Syndrome
Imaging findings
CT shows areas of decreased attenuation (lobular appearance), scattered nodules (some consistent with intrapulmonary lymph nodes), thin-walled cysts in the lung periphery (pauci-cystic disease), and extensive ground glass opacities. Expiratory images confirm air trapping. The cysts are often perivascular and generally rounder than those seen in Birt-Hogg-Dube syndrome.
Key takeaways
Lymphoid interstitial pneumonia (LIP) is a recognized manifestation of Sjögren syndrome, presenting with a combination of ground glass opacities (representing lymphoid aggregates or follicular bronchiolitis), scattered nodules, thin-walled cysts, and air trapping. The ground glass component, rather than the cysts, likely contributes to declining DLCO.
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