CTICasesFibrotic NSIP with Organizing Pneumonia in Scleroderma
Imaging findings
Initial CT demonstrates diffuse parenchymal lung disease with extensive ground glass opacities, consistent with NSIP, alongside superimposed areas suggestive of organizing pneumonia. Over three years, the disease progressed with resolution of much of the dense ground glass and increasing fibrosis, ultimately leading to severely fibrotic lung architecture.
Key takeaways
Non-specific interstitial pneumonia (NSIP) can progress rapidly to severe fibrosis, particularly in the context of connective tissue diseases like Scleroderma. The presence of organizing pneumonia may represent the initial injury that progresses to fibrosis. Severely fibrotic NSIP carries a poor prognosis, often necessitating lung transplantation.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- TAVI Leaflet ThrombusVascular
- RCA Sinoatrial Nodal Branch Fistula Draining to Right AtriumCongenital
- Kawasaki Disease with Coronary Aneurysms and OcclusionsAutoimmune
- Pulmonary Microemboli with Right Heart StrainVascular
- Organizing Pneumonia Progressing to Fibrosis in Rheumatoid ArthritisILD
- Bicuspid Pulmonic Valve with Main Pulmonary Artery EnlargementCongenital
- Aspirated Foreign Body (Almond) Causing Left Lung AtelectasisTrauma
- Milk of Calcium in the Pleural SpaceMetabolic
See all cases from August 28, 2016 →
Related ILD cases
- Lymphoid Interstitial Pneumonia (LIP) related to Sjögren Syndrome
- Progression of NSIP to UIP-like Features in Sjogren's Syndrome
- Organizing Pneumonia and CT Reconstruction Kernel Optimization
- SBRT Radiation Pneumonitis
- Rheumatoid Arthritis-Associated Cystic Lung Disease
- Familial Pleuroparenchymal Fibroelastosis