CTICasesCardiac Amyloidosis with Periatrial Infiltration
Imaging findings
A younger man with biopsy-proven systemic amyloidosis (renal, skin, and elsewhere) has a thickened left ventricle with circumferential myocardial hypoattenuation giving a stiff-heart amyloid appearance on CT. In addition, there is extensive abnormal soft tissue surrounding the left atrium, beyond the usual atrial wall enhancement described in amyloid.
Key takeaways
Cardiac amyloidosis produces a thick, stiff-appearing ventricle with circumferential myocardial hypoattenuation, and beyond the commonly recognized atrial wall involvement it can rarely show extensive periatrial soft-tissue infiltration on CT. Extracellular volume can be quantified by CT (including multiphase mono-energetic techniques, generally with a delayed acquisition), though in a patient with established biopsy-proven amyloid its added utility is limited.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Pulmonary Veno-Occlusive Disease / Pulmonary Capillary HemangiomatosisVascular
- Voriconazole-Induced Skeletal FluorosisMetabolic
- Fat Necrosis of Lipomatous Hypertrophy of the Interatrial SeptumArtifact
- Langerhans Cell HistiocytosisNeoplastic
- Pulmonary Light-Chain Deposition Disease in Waldenstrom MacroglobulinemiaMetabolic
- Sarcoid-Lymphoma Syndrome (Diffuse Large B-Cell Lymphoma)Neoplastic
- Intraparenchymal Chest Tube Placement with Pulmonary HemorrhageIatrogenic
- Intravascular Pulmonary Metastases from OsteosarcomaNeoplastic
See all cases from December 3, 2020 →