CTICasesLoeffler Endocarditis
Imaging findings
Cardiac MRI in a 16-year-old female with hypereosinophilic syndrome (HES) demonstrates diffuse subendocardial late gadolinium enhancement (LGE) and myocardial hyperemia/edema in the right and left ventricles, associated with a small, non-enhancing apical thrombus in the right ventricle.
Key takeaways
Loeffler endocarditis (eosinophilic endomyocardial disease) occurs in patients with hypereosinophilic syndrome. The disease progresses through three stages: an acute necrotic stage (myocardial edema/hyperemia), a thrombotic stage (apical thrombi in the ventricles), and a late fibrotic stage. Cardiac MRI is highly sensitive for depicting subendocardial inflammation and thrombi.
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