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Melody Valve Thrombosis

Imaging findings

CT shows a large, extensive filling defect within a pulmonary conduit Melody valve, consistent with a large thrombus or vegetation, which was associated with an elevated pressure gradient on echocardiography.

Key takeaways

Melody valve (transcatheter pulmonary valve) dysfunction can occur secondary to thrombosis, endocarditis, or a combination of both, presenting as a high gradient and a visible intravascular filling defect. Management often requires surgical conduit replacement and valve explantation.

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