CTICasesChronic Persistent Pulmonary Nodules Post-Blastomycosis
Imaging findings
Chest radiograph and CT show persistent, stable, or slowly evolving pulmonary nodules over several years, some of which demonstrate cavitation and peripheral mineralization or calcification.
Key takeaways
While pulmonary nodules from blastomycosis typically resolve after therapy, they can occasionally persist and calcify over time, mimicking histoplasmosis. Chronic treatment with antifungals like itraconazole for 9 to 12 months is standard, and monitoring urine antigen levels can help confirm resolution of active infection.
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