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Lupus-associated diffuse alveolar hemorrhage

Imaging findings

CT scan of an SLE patient shows patchy, nodular ground-glass opacities and areas of consolidation. Bronchoscopy confirmed diffuse alveolar hemorrhage (DAH) showing fresh blood and hemosiderin-laden macrophages.

Key takeaways

Diffuse alveolar hemorrhage is a rare, life-threatening manifestation of SLE. It is caused by pulmonary capillaritis or vasculitis and typically presents with patchy or diffuse ground-glass opacities, drop in hematocrit, and hypoxia, even in the absence of hemoptysis.

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