CTICasesChronic Eosinophilic Pneumonia with Residual Fibrosis
Imaging findings
Initial CT chest shows discrete, lobule-conforming ground-glass opacities with sharp interfaces against normal lung parenchyma in a patient with peripheral eosinophilia. A follow-up CT scan 10 years later reveals persistence of these same patchy ground-glass areas, now associated with small cystic spaces, dilated airways, and focal traction bronchiectasis.
Key takeaways
While acute or typical chronic eosinophilic pneumonia usually resolves rapidly and completely with corticosteroid therapy, some cases can exhibit a long-standing, persistent, or relapsing course. If inadequately treated, chronic eosinophilic inflammation can lead to irreversible parenchymal remodeling, including focal fibrosis, traction bronchiectasis, and cystic changes.
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