CTICasesInflammatory pseudotumor of the lung in scleroderma
Imaging findings
Chest CT in a patient with severe scleroderma demonstrates a new, non-calcified, slightly lobulated nodule in the right lung with low FDG-PET avidity. Histopathology of the resected nodule confirmed a lymphoplasmacytic type of inflammatory pseudotumor with an elevated IgG4 ratio.
Key takeaways
Inflammatory pseudotumors (plasma cell granulomas) are rare, benign pulmonary lesions that can occur in the setting of autoimmune diseases like scleroderma or IgG4-related disease. They should be considered in the differential diagnosis of a new lung nodule in these patients.
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