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Granulomatosis with polyangiitis

Imaging findings

CT of the paranasal sinuses shows extensive sinus disease. Chest CT shows circumferential thickening of the lower tracheal wall, stenosis of the left main bronchus and bronchus intermedius, and mucosal thickening of the right upper lobe bronchus, with sparing of the lung parenchyma.

Key takeaways

Granulomatosis with polyangiitis can involve the airways in up to 50% of patients. Manifestations include subglottic stenosis, circumferential wall thickening, and narrowing of the mainstem and lobar bronchi, which can occur independently of active parenchymal disease.

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