CTICasesGranulomatous-lymphocytic interstitial lung disease
Imaging findings
Serial chest CT scans in a patient with common variable immunodeficiency show multiple bilateral, waxing and waning pulmonary nodules with surrounding ground-glass halos, along with areas of pure ground-glass attenuation. Lymph node biopsy demonstrated non-necrotizing granulomas.
Key takeaways
Granulomatous-lymphocytic interstitial lung disease is a rare, non-infectious pulmonary complication of common variable immunodeficiency. It typically presents as multiple waxing and waning nodules or ground-glass opacities, and biopsy is required to distinguish it from lymphoma or active infection.
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