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Silicotuberculosis

Imaging findings

CT chest in a former miner shows multiple small, calcified, perilymphatic nodules in the upper lobes, conglomerate masses with progressive massive fibrosis (PMF), and a large, thick-walled cavity in the right apex with tracheal deviation, representing silicotuberculosis.

Key takeaways

Silicosis is a well-established, potent risk factor for tuberculosis (silicotuberculosis) due to silica-induced impairment of alveolar macrophage function. The development of cavitation, rapid progression of nodules, or constitutional symptoms in a patient with silicosis should always raise suspicion for active TB.

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