CTICasesFollicular Bronchiolitis Associated with Asthma
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Imaging findings
A 43-year-old woman with a chronic history of asthma presented with bronchial wall thickening and scattered ground glass nodules, some with central airways, that progressed with solid components over six years. VATS biopsy confirmed follicular bronchiolitis in multiple nodules.
Key takeaways
Follicular bronchiolitis is a lymphoid hyperplasia within the lung, considered part of a spectrum including nodular lymphoid hyperplasia and lymphocytic interstitial pneumonia. While typically associated with connective tissue diseases or immune deficiencies (e.g., HIV), this case highlights its rare occurrence in the context of severe, long-standing asthma, suggesting that chronic airway inflammation may contribute to its development, even without an overt autoimmune disorder.
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