CTICasesAcquired Cystic Lung Disease/Emphysema in Amyloidosis
Imaging findings
A patient with AL amyloidosis developed progressive cystic changes, particularly in the lingula, and generalized lung tissue loss (emphysema) over several years.
Key takeaways
Protein deposition in the lungs in amyloidosis can lead to acquired emphysema, likely due to macrophage-associated matrix metalloproteinase activity degrading the ground substance.
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