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Pulmonary Amyloidosis (Cystic and Calcified)

Imaging findings

Chest CT shows multiple thin-walled parenchymal lung cysts. Notably, these cysts feature robust, irregular, chunky calcification directly along their walls and margins, without other soft-tissue nodules.

Key takeaways

Pulmonary amyloidosis can present with various radiologic manifestations, including nodular, tracheobronchial, or diffuse interstitial patterns. The cystic form of pulmonary amyloidosis represents localized protein deposition that causes alveolar wall destruction. A classic diagnostic clue for amyloid-associated cysts is the presence of focal calcification or ossification within the walls of the cysts.

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