CTICasesRenal Osteodystrophy with Vertebral Brown Tumor
Imaging findings
CT of the thoracic spine shows classic features of renal osteodystrophy, including a rugger-jersey spine characterized by dense sclerotic bands at the upper and lower endplates of the vertebral bodies with relative central lucency. There is also a lytic, destructive lesion in one of the softened vertebral bodies, highly suggestive of a brown tumor in the setting of secondary hyperparathyroidism.
Key takeaways
Renal osteodystrophy in chronic renal failure typically presents with a rugger-jersey spine, subperiosteal resorption, and soft bone disease. Osteoclast activation driven by secondary hyperparathyroidism can lead to focal lytic, osteoclastic bone lesions known as brown tumors, which can affect the vertebral bodies or ribs and should not be mistaken for metastatic disease.
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