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Idiopathic Dendriform Pulmonary Ossification

Imaging findings

Chest CT demonstrates progressive, branching, calcified and ossified structures within the lung parenchyma bilaterally, consistent with dendriform pulmonary ossification. There is also significant hyperinflation, airways disease, and severe rarefaction of the anterior pulmonary vasculature, suggesting underlying constructive bronchiolitis or severe small airways obstruction.

Key takeaways

Dendriform pulmonary ossification is characterized by branching bone formation within the lung parenchyma. While it is commonly associated with chronic lung injury, chronic aspiration, or fibrosing lung disease such as usual interstitial pneumonia, idiopathic forms exist and can present with progressive symptoms. In patients with significant hyperinflation and vascular rarefaction, associated small airways disease or constrictive bronchiolitis should be considered as the primary source of symptoms.

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