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Granulomatosis with Polyangiitis (Wegener's) with Tracheobronchial Involvement

Granulomatosis with Polyangiitis (Wegener's) with Tracheobronchial Involvement▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Nodular and segmental thickening of the tracheal wall, with similar nodular thickening and narrowing of the left mainstem bronchus. A soft tissue density lesion was also noted in the left lower lobe.

Key takeaways

Tracheobronchial involvement with nodular wall thickening and narrowing is a less common but important manifestation of Granulomatosis with Polyangiitis (Wegener's). Patients typically have positive c-ANCA and systemic symptoms like hearing loss and mastoiditis.

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