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MALT lymphoma

Imaging findings

Chest CT shows multiple solid and ground-glass pulmonary nodules of varying sizes in a young, healthy non-smoking woman, associated with enlarged hilar and mediastinal lymph nodes. Biopsy of a nodule confirmed extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue.

Key takeaways

Primary pulmonary MALT lymphoma is a low-grade B-cell lymphoma that typically arises in the context of chronic immune stimulation. While often presenting in patients with Sjogren's syndrome or other autoimmune conditions, it can occur in young, healthy individuals as solitary or multicentric nodules.

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