CTICasesSmall cell lung carcinoma
Imaging findings
Chest CT shows a small, growing soft tissue density in a lymph node located immediately posterior to the left pulmonary artery, which demonstrated intense FDG uptake on PET CT. Biopsy of the node confirmed a stage 1 small cell lung carcinoma.
Key takeaways
Lung cancer screening cohorts remain at high risk for developing aggressive interval malignancies, including small cell carcinoma, even after prior negative screens. Recognizing subtle, growing mediastinal or hilar lymphadenopathy on screening CT is critical for early detection.
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