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Post-transplant lymphoproliferative disorder

Imaging findings

Chest CT in a single lung transplant recipient shows a solitary pulmonary nodule with a surrounding ground-glass halo (CT halo sign) in the right allograft. Biopsy confirmed EBV-positive post-transplant lymphoproliferative disorder.

Key takeaways

Post-transplant lymphoproliferative disorder (PTLD) can manifest pulmonarily as single or multiple nodules, occasionally presenting with a surrounding ground-glass halo, mimicking fungal infection (such as Aspergillus or Cryptococcus).

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