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Pulmonary Parenchymal Extramedullary Hematopoiesis

Imaging findings

Chest CT shows chronic, stable, diffuse ground-glass opacities with focal lobular sparing in a patient with myelofibrosis and abnormal bones, consistent with pulmonary extramedullary hematopoiesis.

Key takeaways

Extramedullary hematopoiesis can rarely involve the lung parenchyma directly. It presents as chronic, stable, diffuse ground-glass opacities with lobular sparing, and must be differentiated from chronic edema or alveolar proteinosis.

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