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Cystic Pulmonary Metastases from Urothelial Carcinoma

Imaging findings

Surveillance chest CT shows the rapid development of multiple thin-walled, well-defined cystic lesions and a few ground-glass nodules predominantly in the upper lobes, which grew and became more irregular on a follow-up scan two months later. Biopsy confirmed metastatic urothelial carcinoma.

Key takeaways

Urothelial (bladder) carcinoma metastases can present as rapidly progressive, thin-walled cystic lesions in the lungs. Because urothelial tumors share squamous characteristics, they can undergo rapid liquefaction necrosis and cough out, resulting in early cavitary changes and mimicking primary cystic lung diseases.

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