CTICasesCarcinoid heart disease
Imaging findings
Echocardiography and cardiac MRI show marked thickening, stiffness, and retraction of the tricuspid valve leaflets causing severe regurgitation, along with thickening and restricted opening of the pulmonic valve leaflets, in a patient with metastatic neuroendocrine tumor of the small bowel and multiple liver metastases.
Key takeaways
Carcinoid heart disease is a rare manifestation of carcinoid syndrome. Serotonin released by hepatic metastases causes plaque-like fibrous thickening of the endocardium, typically involving the tricuspid and pulmonic valves on the right side of the heart, resulting in valvular stenosis and regurgitation.
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