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Pulmonary mycobacterial spindle cell pseudotumor

Imaging findings

Chest CT shows an endoluminal soft tissue mass in the bronchus intermedius causing complete obstruction and collapse of the right middle lobe. Histopathology revealed a spindle cell proliferation rich in acid-fast bacilli, confirming a mycobacterial spindle cell pseudotumor.

Key takeaways

Mycobacterial spindle cell pseudotumor is a rare, tumor-like reaction to atypical mycobacteria, typically occurring in immunocompromised patients (such as those with HIV). It pathologically mimics a spindle cell neoplasm but is diagnostic on acid-fast staining.

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