CTICasesPulmonary leukemia relapse
Imaging findings
Serial chest CT scans over 2 weeks show rapid progression and enlargement of multiple bilateral pulmonary nodules with surrounding ground-glass halos, some nodules showing perilymphatic and major fissure distribution. Lung biopsy confirmed infiltration by acute myeloid leukemia.
Key takeaways
Pulmonary relapse of acute myeloid leukemia can present atypically as rapidly growing nodules with surrounding ground-glass halos, mimicking opportunistic fungal infections. Tissue biopsy is critical to distinguish leukemic infiltration from infection.
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