CTICasesPulmonary Trichoderma Infection
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Imaging findings
High-resolution CT chest in a neutropenic patient with natural killer cell leukemia demonstrates multiple fuzzy, dense pulmonary nodules surrounded by a halo of ground-glass opacity, representing the classic "halo sign."
Key takeaways
While the halo sign in a neutropenic patient strongly suggests angioinvasive aspergillosis, it can be caused by other opportunistic molds. In this case, the causative pathogen was Trichoderma citrinoviride, a soil fungus and well-known contaminant of illegally cultivated marijuana. Smoking contaminated marijuana in immunocompromised patients represents a dangerous vector for invasive fungal infections.
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See all cases from March 25, 2016 →