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Allergic Bronchopulmonary Aspergillosis (ABPA)

Allergic Bronchopulmonary Aspergillosis (ABPA)▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Chest radiograph shows tubular branching opacities radiating from the hilum in a "finger-in-glove" configuration, primarily in the upper lobes. High-resolution CT shows central bronchiectasis with high-attenuation mucoid impaction and surrounding areas of consolidation or post-obstructive changes.

Key takeaways

ABPA is a hypersensitivity reaction to colonization by Aspergillus fumigatus, classically occurring in patients with asthma or cystic fibrosis. The hallmark imaging finding is central bronchiectasis containing thick mucus plugs, which often demonstrate high CT attenuation due to calcium and manganese deposition by the fungus. Treatment involves oral corticosteroids to suppress the immune response, often combined with antifungal therapy.

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