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Smoking-related emphysema with expiratory collapse

Imaging findings

Chest CT shows severe centrilobular and paraseptal emphysema with a large, atypical cystic/emphysematous space in the left upper lobe that communicates directly with adjacent dilated airways. Expiratory CT demonstrates near-complete collapse of this emphysematous space.

Key takeaways

While emphysematous spaces typically do not change size significantly due to airway destruction and air trapping, some large smoking-related emphysematous spaces can collapse on expiration if they retain direct communication with patent, non-obstructed airways.

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