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Nocardia cyriacigeorgica pneumonia

Imaging findings

Chest CT in a stem cell transplant recipient shows bilateral, large, necrotic consolidative masses and multiple smaller nodules, some demonstrating internal cavitation, in a patient with graft-versus-host disease on steroid therapy.

Key takeaways

Nocardia cyriacigeorgica is an opportunistic pathogen in immunocompromised hosts, such as stem cell transplant recipients. It classically presents as large, necrotic mass-like lesions or cavitating nodules, and standard prophylaxis with trimethoprim-sulfamethoxazole is typically protective.

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