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Coccidioidomycosis Mimicking Sarcoidosis

Coccidioidomycosis Mimicking Sarcoidosis▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A patient presenting with neck pain, fatigue, night sweats, dyspnea, and palpable lymphadenopathy shows enlarged mediastinal and hilar lymph nodes on CT. Lung windows reveal tiny perilymphatic nodules clustered in the left upper lobe. A PET scan showed uptake in these nodes.

Key takeaways

The imaging findings, including enlarged mediastinal/hilar lymph nodes and perilymphatic nodules, strongly mimicked sarcoidosis. However, a mediastinal lymph node biopsy grew out Coccidioides, illustrating how coccidioidomycosis can present with sarcoid-like imaging features.

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