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Nocardia Nova in a Heart Transplant Patient

Nocardia Nova in a Heart Transplant Patient▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Initial CT showed a small incidental lesion on the surface of the heart, a few months post-transplantation. Follow-up CT two months later showed growth of this lesion and new nodules in the right lung base, along with some tree-in-bud opacities. The lesion became visible on chest radiograph as a round lesion adjacent to the heart. The lesion was needled and grew out Nocardia nova.

Key takeaways

Nocardia (specifically Nocardia nova) is a common cause of lung nodules in solid organ transplant patients with modest immune suppression. These nodules can be relatively asymptomatic and show slow growth over months. They can also cavitate. Nocardia is a pathogenic organism, never a commensal in humans.

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