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Neovascularity of Pulmonary Hypertension

Imaging findings

CT chest shows severe pulmonary arterial hypertension with corkscrew-like peripheral pulmonary vessels and ground-glass tufts. Bronchial arteriography shows massively dilated bronchial artery collaterals.

Key takeaways

Familial pulmonary arterial hypertension (often associated with BMPR2 mutations) can cause neovascularity of the lung parenchyma. This manifests as highly tortuous corkscrew vessels and centrilobular micro-aneurysms that bleed, causing hemoptysis that can be treated by bronchial artery embolization.

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