CTICasesAnterior Mediastinal Mature Teratoma with Prior Rupture and Inflammation
[...]. Anterior Mediastinal Mature Teratoma with Prior Rupture and Inflammation. CTICases. Published August 5, 2016. https://cticases.com/c/eypn6
Imaging findings
Radiograph shows an anterior mediastinal mass (a "mogul" or opacity). CT confirms an anterior mediastinal mass with areas of low attenuation (fat/fluid) and internal heterogeneity, contiguous with the pericardium and surrounded by fat. Pathology revealed a mature teratoma with evidence of prior rupture and marked inflammation, including granulation tissue reaction.
Key takeaways
Anterior mediastinal teratomas can present with internal heterogeneity, including low attenuation components (fat/fluid), and may rupture, leading to acute symptoms (like chest discomfort) and a surrounding inflammatory reaction. Pathological findings can confirm evidence of prior rupture and associated inflammation. The "4 T's" (Teratoma, Thymoma, Thyroid, Lymphoma) are the classic differential for anterior mediastinal masses.
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