CTICasesMetastatic Malignant Uterine PEComa
Imaging findings
Chest radiograph and chest CT demonstrate multiple pulmonary nodular metastases of different sizes, some of which show spontaneous cavitation and internal necrosis (foci of low attenuation). Biopsy confirmed metastatic perivascular epithelioid cell tumor (PEComa) originating from the uterus.
Key takeaways
PEComas (perivascular epithelioid cell tumors) are a rare family of mesenchymal tumors that include angiomyolipomas, lymphangioleiomyomatosis (LAM), and clear cell sugar tumors of the lung. While many are benign, malignant uterine PEComas are aggressive neoplasms that can metastasize to the lungs, presenting as cavitary or necrotic pulmonary nodules.
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