CTICasesCellCept-Induced Pneumatosis Intestinalis
Imaging findings
Abdominal CT in a lung transplant patient (status post clamshell sternotomy) shows extensive pneumatosis intestinalis involving the bowel wall, which had been present and slowly progressing for several months. Surgical laparoscopy confirmed that the bowel was completely viable with no signs of ischemia, representing benign pneumatosis.
Key takeaways
Pneumatosis intestinalis (gas in the bowel wall) is a concerning sign for bowel ischemia but can be benign, particularly in patients on immunosuppression. Mycophenolate mofetil (CellCept) is a known cause of benign pneumatosis intestinalis in transplant recipients, which resolves upon drug discontinuation without surgical resection.
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