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Adrenal Ganglioneuroma

Imaging findings

MRI of the abdomen demonstrates a large right adrenal mass with heterogeneous T2 signal, areas of low signal, and streaky enhancement on post-contrast sequences, without restricted diffusion. CT shows a well-circumscribed lesion with foci of calcification, lower attenuation than a cortical carcinoma, and no local invasion. Pathology confirmed a ganglioneuroma.

Key takeaways

Ganglioneuromas are benign, fully differentiated tumors arising from the sympathetic chain. Although classically presenting as elongated posterior mediastinal masses, they can rarely arise within the adrenal gland. On MRI, they typically show heterogeneous T2 signal and lack the rapid arterial enhancement characteristic of adrenocortical carcinoma or pheochromocytoma.

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