CTICasesUnclassifiable Interstitial Lung Disease
Imaging findings
CT chest shows a progressive interstitial lung disease with lower-lobe reticulation, ground-glass opacities, traction bronchiectasis, and air trapping on expiratory CT, with a dearth of subpleural predominance or honeycombing (indeterminate for UIP). Pathology showed heterogeneous fibrosis and NSIP-like areas.
Key takeaways
Unclassifiable interstitial lung disease (ILD) represents a subset of patients who exhibit overlapping clinical, radiographic, and pathological features that do not fit into a single established category (like UIP or NSIP). These patients are managed with anti-fibrotics or immunosuppression based on the dominant clinical pattern.
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