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Intrapulmonary Lymph Nodes Involved with Lymphoma

Intrapulmonary Lymph Nodes Involved with Lymphoma▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Initial CT showed several subpleural, ovoid or polygonal nodules in the right middle lobe and other locations, resembling intrapulmonary lymph nodes, with only subcentimeter mediastinal lymph nodes. A follow-up study, performed due to recurrent symptoms (B symptoms) in a patient with a history of B-cell lymphoma, revealed increased size of mediastinal and internal jugular chain lymph nodes. Crucially, the previously identified intrapulmonary nodules also enlarged and maintained their characteristic morphology.

Key takeaways

This case illustrates the involvement of intrapulmonary lymph nodes by systemic lymphoma. While initially appearing as benign intrapulmonary lymph nodes, their enlargement concurrently with other lymphatic disease in a patient with recurrent lymphoma confirms malignant infiltration. This highlights that intrapulmonary lymph nodes, like their mediastinal counterparts, can be affected by lymphoproliferative disorders.

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