CTICasesMultiple Large Histoplasmomas
Imaging findings
CT shows multiple pulmonary nodules, each with a soft-tissue rim and dense central, sometimes ring-like or target-like, calcification, including unusually large examples in the middle lobe. The nodules grew slowly over multiple years. No splenic calcifications were shown in this particular case.
Key takeaways
Histoplasmomas typically appear as nodules with dense central or target-like calcification meeting benign criteria, and in endemic regions multiple and unusually large histoplasmomas can occur and slowly enlarge, so following them is unnecessary. They may show mild FDG activity, and the differential for this central-calcification pattern includes tuberculoma and dirofilariasis (dog heartworm), which favors smooth basal nodules; associated splenic calcifications and mediastinal nodes favor histoplasmosis.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Transdiaphragmatic Air via the Foramen of Morgagni (Macklin Phenomenon)Artifact
- Fibrotic Hypersensitivity PneumonitisILD
- Fibrotic Hypersensitivity Pneumonitis with GranulomasILD
- Hypervascular Atrioventricular-Groove Lesion (Suspected Paraganglioma)Neoplastic
- E-Cigarette or Vaping-Associated Lung Injury (EVALI)Exposure
- Coronary Sinus Ostial Atresia with Anomalous Venous DrainageCongenital
- Giant Posterior Mediastinal ParagangliomaNeoplastic
- Tracheomalacia on Dynamic Expiratory CTOther
See all cases from January 15, 2021 →