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Nodular Pulmonary Amyloidosis

Imaging findings

CT chest followed over 3 years shows stable, multiple bilateral pulmonary nodules and masses, with progressive calcification/ossification involving the mass in the right lower lobe. Biopsy confirmed AL light chain amyloid deposits.

Key takeaways

Nodular pulmonary amyloidosis is characterized by single or multiple amyloid tumors in the lung parenchyma. These nodules are typically slow-growing or stable over years and frequently undergo calcification or metaplastic ossification. Unlike diffuse alveolar septal amyloidosis, the nodular form has a benign prognosis.

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