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E-cigarette or Vaping Product Use-Associated Lung Injury

Imaging findings

CT chest shows bilateral, fuzzy, centrilobular ground-glass nodules and patchy consolidations, associated with prominent mediastinal and hilar lymphadenopathy. The patient had four negative COVID-19 tests and a history of heavy marijuana/THC vaping. The findings cleared rapidly with corticosteroids.

Key takeaways

E-cigarette or vaping product use-associated lung injury (EVALI) can present with cough, fever, and dyspnea, mimicking infectious atypical pneumonias such as COVID-19. Key CT features include diffuse ground-glass opacities, centrilobular nodules, and sometimes subpleural sparing. Rapid clinical and radiographic improvement with systemic corticosteroids is characteristic.

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