CTICasesLymphomatoid granulomatosis
Imaging findings
CT and PET/CT show multiple hypermetabolic, cavitating pulmonary nodules of varying sizes in both lungs, in a patient with a history of Crohn's disease treated with azathioprine, presenting with a biopsy-confirmed EBV-positive scalp lesion.
Key takeaways
Lymphomatoid granulomatosis is a rare EBV-associated lymphoproliferative disorder. It is strongly linked to iatrogenic immunodeficiency (such as from azathioprine) and typically manifests as multiple cavitating pulmonary nodules, skin lesions, and neurological deficits.
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