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Rapidly Progressive Fibrosis in ANCA-Associated Vasculitis

Imaging findings

CT chest shows rapidly progressive basilar-predominant reticulation, ground-glass opacities, and bronchiectasis over 11 months, with mixed central consolidative bands and large parenchymal nodules.

Key takeaways

ANCA-associated vasculitis (specifically microscopic polyangiitis) can be associated with interstitial lung disease and progressive pulmonary fibrosis. While typically slow-growing, it can show rapid progression over months and must be included in the differential of rapidly progressive fibrotic lung disease.

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