CTICasesThymic Lymphoid Hyperplasia Invaginating the Mediastinum
Imaging findings
CT chest shows a large, homogeneous, soft tissue mass in the anterior mediastinum that invaginates between the ascending aorta and the superior vena cava, showing moderate FDG avidity on PET. Surgical biopsy confirmed benign thymic lymphoid hyperplasia.
Key takeaways
Thymic lymphoid hyperplasia is characterized by the presence of numerous lymphoid germinal centers within the thymus, commonly associated with autoimmune conditions such as myasthenia gravis, Graves' disease, or Hashimoto's thyroiditis. Radiographically, it presents as thymic enlargement, which can atypically invaginate between major mediastinal vessels.
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