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Actinomyces Odontolyticus Septic Emboli

Imaging findings

CT chest shows multifocal, bilateral centrilobular tree-in-bud nodules and small, solid cavitary nodules in a patient with a history of intravenous drug abuse and a chronic indwelling central line. Blood cultures grew Actinomyces odontolyticus, and biopsy confirmed septic emboli.

Key takeaways

Actinomyces odontolyticus is a member of the normal oral flora. In intravenous drug users who crush or dissolve oral pills and inject them (sometimes utilizing saliva or oral manipulation), the bacteria can be injected into the venous system, seeding the lungs as septic emboli (excipient lung disease).

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